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Sanakin® 

Sanakin ® (ACRS) serum is one of the newest complementary laboratory methods that can be used by anyone who wants to maximize the positive outcome of infertility treatment. It is an autologous conditioned serum rich in cytokines that are essential for optimizing reproductive function, suppressing inflammation, and supporting the success of the IVF process.

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What are the benefits of the Sanakin® method ?

  • It modifies the uterine lining before a healthy embryo is inserted so that it will nest properly
  • It works as a fertility support, increasing the quality of oocytes and endometrium using its own cells.
  • It increases the success rate of healthy embryo implantation and IVF cycles.
  • By using its own biological material, it minimizes the risk of allergic reactions and thus ensures a natural and safe treatment.
  • To achieve the best results and complexity of care, it is recommended to combine Sanakin® (ACRS) serum with other supportive methods of infertility treatment.

At Prague Fertility Centre we inject the serum only into the uterus

Method of preparation and administration of Sanakin serum® 

The scheme of the treatment procedure:


  • Consultation — An initial interview with an IVF specialist and an examination are necessary to begin therapy.
  • Blood collection — The nurse will take a blood sample from the patient’s vein.
  • Blood incubation — Blood is then incubated with subsequent overproduction of anti-inflammatory agents. The process takes 3 hours where your blood cells come into contact with the glass beads in the Sanakin® tube. The blood cells are stimulated at 37°C to increase the production of cytokines (anti-inflammatory interleukins and growth factors).
    Application of Sanakin® (ACRS) serum - The serum is injected through a thin catheter into the uterine cavity on the same day as the blood collection

Who is Sanakin® (ACRS) serum suitable for? 

  • for patients who have undergone several unsuccessful embryo transfers
  • for women with low uterine lining (endometrium)
  • for patients suffering from chronic inflammation of the uterus — in these cases Sanakin® serum adjusts the conditions in the uterine lining

Other laboratory methods that can increase the success rate of treatment 

Laboratory methods

Egg fertilisation: OptimFert 

An innovative polarising microscopy method for monitoring egg maturity to determine the correct timing for fertilisation.

PGT‑M, PGT-SR & PGT‑A

Preimplantation genetic screening and diagnosis — prevention of nesting failure and transmission of genetic defects.

Embryo nesting support: LAZT 

Laser-assisted hatching is a non-invasive method for facilitating an embryo to leave the protective shell and promote nesting.

Sperm selection: MICHSS 

Selection of the best quality sperm based on concentration and motility using a microfluidic chip.

Egg fertilisation: ICSI 

Intracytoplasmic injection of sperm directly into the egg in order to overcome barriers and increase chances of fertilisation.

Extended embryo culturing 

Monitored embryo development over 48 hours to select the embryo with the highest potential for implantation.

Embryo nesting support: EmbryoGlue 

A special solution for protecting the embryo and facilitating its connection with the uterine lining.

Endometrium receptivity test 

ERA test, beReady — advanced analytical methods of the genetic profile of the uterine lining to determine the timing of implantation.

ASET 

Asynchronous embryo transfer is a method in which we transfer 2 embryos of different ages to increase chances of succesful implantation.

Preservation of cells: Vitrification 

Preservation of eggs and embryos for potential future use by fast, gentle and efficient freezing.

Sperm selection: LAISS 

Detection of viable sperm in a non-motile sample using a non-invasive laser.

Sperm retrieval: MESA/TESE

Modern microsurgical sperm collection methods from the testicles and epididymis in the case of low / zero sperm concentration.
Laboratory methods